FAB 22 – Williamsport – Philadelphia
| Est. Time | |||
| Williamsport, PA (Fullington Trailways, 11 West Church Street) | SR, T | 2:15 PM | |
| Watsontown, PA (144 Main St.) | OC | Discharge only, on call | 2:35 PM |
| Milton, PA (83 Broadway St.) | OC | Discharge only, on call | 2:45 PM |
| Lewisburg, PA (505 Market Street, bus stops at RR tracks) | SR | Flag Stop | 2:55 PM |
| Sunbury, PA (Stop: Woodlawn Ave., next to Burger King) (Ticket Sales: Nationwide Insurance, 519 Market St.) |
SR, T | 3:25 PM | |
| Shamokin, PA Penn Jersey Food Mart, 61 E. Independence St) | SR, T | 3:55 PM | |
| Kulpmont, PA (Corner of Chestnut St., Rt. 61 & 6 th St.) | SR | Flag Stop | 4:00 PM |
| Mt. Carmel, PA (Corner of 5 th & S. Oak St) | SR | Flag Stop | 4:10 PM |
| Ashland, PA (706 Centre St, Smokin’ Joes Tobacco Shop) | SR | Flag Stop | 4:25 PM |
| Frackville, PA (accros from Wells Fargo Bank, S. Lehigh Ave. & Frack St.) | SR | Flag Stop | 4:35 PM |
| Shenandoah, PA (Stop: 125 E Center St.) | SR | Flag Stop | 4:40 PM |
| Mahanoy City, PA (10 W. Centre St, in front of Mahanoy Elderly) | SR | Flag Stop | 4:50 PM |
| Hometown, PA (Just before intersection of Rtes. 54 & 309, alongside Dunkin Donuts) | SR | Flag Stop | 5:00 PM |
| Tamaqua, PA (Corner of Broad & Greenwood Sts., Eastbound Side) | SR | Flag Stop | 5:10 PM |
| Coaldale, PA (E. Water St. & First St., across from White School Bus Shed) | SR | Flag Stop | 5:15 PM |
| Lansford, PA (in front of Turkey Hill, 22 W. Patterson St.) | SR | Flag Stop | 5:20 PM |
| Nesquehoning, PA (74 W. Catawissa St.) | SR | Flag Stop | 5:25 PM |
| Jim Thorpe, PA (in front of Subway, 5 Lehigh Ave) | SR | Flag Stop | 5:35 PM |
| Lehighton, PA (Giant Plaza, behind McDonalds, Rte. 443) | SR | 6:00 PM | |
| Allentown, PA (325 W. Hamilton St.) | SR, T | 6:40 PM | |
| Quakertown, PA (in front of Burger King, 100 N. West End Blvd) | SR | Flag Stop | 6:55 PM |
| Doylestown, PA (Trans-bridge Bus Stop, S. Clinton St. & Bridge St.) | SR | Flag Stop | 7:20 PM |
| Abington (Willow Grove), PA (in front of gas station at coner of Rockwell & Rte 611, across from PNC Bank) |
SR | Flag Stop | 7:50 PM |
| Philadelphia, PA (Greyhound Terminal, 1001 Filbert St.) | SR, T | 8:40 PM |
- SR – Scheduled Routes
- T – Ticket Sales Available
- OC – Discharge / On Call Only: Must call 888-847-2430 24 hours in advance for pick-up.
- Flag Stop – Must be on side of road, flagging bus down as passes.